PCR typing of field isolates of Plasmodium falciparum
نویسندگان
چکیده
منابع مشابه
pfcrt gene in plasmodium falciparum field isolates from muzaffargarh, pakistan
background : the aim of the study was to identify the prevalence of different species of plasmodium and haplotypes of pfcrt in plasmodium falciparum from the selected area. methods : overall, 10,372 blood films of suspected malarial patients were examined microscopically from rural health center sinawan, district muzaffargarh, pakistan from november 2008 to november 2010. p. falciparum positive...
متن کاملComparative Transcriptional and Genomic Analysis of Plasmodium falciparum Field Isolates
Mechanisms for differential regulation of gene expression may underlie much of the phenotypic variation and adaptability of malaria parasites. Here we describe transcriptional variation among culture-adapted field isolates of Plasmodium falciparum, the species responsible for most malarial disease. It was found that genes coding for parasite protein export into the red cell cytosol and onto its...
متن کاملPfcrt Gene in Plasmodium falciparum Field Isolates from Muzaffargarh, Pakistan
BACKGROUND The aim of the study was to identify the prevalence of different species of Plasmodium and haplotypes of pfcrt in Plasmodium falciparum from the selected area. METHODS Overall, 10,372 blood films of suspected malarial patients were examined microscopically from rural health center Sinawan, district Muzaffargarh, Pakistan from November 2008 to November 2010. P. falciparum positive s...
متن کاملRESISTANCE OF PLASMODIUM FALCIPARUM TO CHLOROQUINE IN SOUTH EASTERN IRAN
In vivo and in vitro assessments of the response of P. falciparum to chloroquine using WHO standard kits and techniques were carried out in I ran Shahr, Sistan and Baluchestan province of Iran in 1985. In the in vivo assessment, 24 malaria patients treated with chloroquine (25mg/kg over three days) were followed up for one to four weeks. The mean parasite clearance time was 4.3 days and in...
متن کاملWhole-transcriptome analysis of Plasmodium falciparum field isolates: identification of new pathogenicity factors.
BACKGROUND Severe malaria and one of its most important pathogenic processes, cerebral malaria, involves the sequestration of parasitized red blood cells (pRBCs) in brain postcapillary venules. Although the pathogenic mechanisms underlying malaria remain poorly characterized, it has been established that adhesion of pRBCs to endothelial cells (ECs) can result in cell apoptosis, which in turn ma...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1995
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.33.4.944-951.1995